Formulation: A solid
Formal Name: 3,7-dihydro-7-(2-hydroxyethyl)-1,3-di(methyl-d3)-1H-purine-2,6-dione
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C9H6D6N4O3
Formula Weight: 230,3
Shelf life (days): 1460
Notes: 7-(β-Hydroxyethyl)theophylline-d6 is intended for use as an internal standard for the quantification of 7-(β-hydroxyethyl)theophylline (Item No. 28372) by GC- or LC-MS. 7-(β-Hydroxyethyl)theophylline is a methylxanthine phosphodiesterase (PDE) inhibitor.{53088} It reduces histamine, 5-hydroxytryptamine (5-HT), and bradykinin-induced bronchoconstriction in an anesthetized guinea pig model of bronchial asthma.{53089} Formulations containing 7-(β-hydroxyethyl)theophylline in combination with theophylline have been used in the treatment of asthma.