Formulation: A solid
Formal Name: 8-chloro-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Purity: ≥98%
Formula Markup: C8H9ClN4O2
Formula Weight: 228,6
Shelf life (days): 1460
CAS Number: 4921-49-7
Notes: 8-chloro Caffeine is a derivative of the methylxanthine alkaloid caffeine (Item No. 14118). It binds to adenosine receptors (apparent Ki = 30 µM).{67136} 8-chloro Caffeine (250 µM) potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells.{67137} It has also been used in the synthesis of mixed lineage kinase domain-like protein (MLKL) inhibitors with necroptosis-inhibiting activity.{59296}