Formulation: A solid
Formal Name: S-(acetate-d3) coenzyme A, sodium salt
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C23H35D3N7O17P3S • XNa
Formula Weight: 812,6
Shelf life (days): 1460
Notes: Acetyl-coenzyme A-d3 (acetyl-CoA-d3) is intended for use as an internal standard for the quantification of acetyl-CoA (Item No. 16160) by GC- or LC-MS. Acetyl-CoA, the thioester of CoA (Item Nos. 16147 / 21499 / 21722) and acetic acid, is a pivotal molecule in biological systems. Foremost, it serves as a source of carbon for the Krebs cycle, for the synthesis of fatty acids, and for isoprenoid-based protein modifications.{26418,26416,26417,26415} Acetyl-CoA also serves as an intermediate in oxidation of fatty acids and amino acids and is formed by the oxidative decarboxylation of pyruvate in mitochondria.{26414} It is an essential cofactor or substrate for acetyltransferases and acyltransferases, as in the post-translational modification of proteins and in the synthesis of the neurotransmitter acetylcholine.{26416,26417}
English
Deutsch
