Formulation: A solid
Formal Name: adenosine 5′-(trihydrogen diphosphate), P′→5-ester with 4-nitrophenyl β-D-ribofuranoside, disodium salt
Purity: ≥98%
Formula Markup: C21H24N6O16P2 • 2Na
Formula Weight: 724,4
Shelf life (days): 730
Notes: Adenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) is a nitrophenyl ribose-modified nucleotide and colorimetric substrate for poly(ADP-ribose) polymerase 1 (PARP1).{69281} PARP1 binds and hydrolyzes adenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) to release p-nitrophenol, which can be quantified by colorimetric detection at 405 nm as a measure of PARP1 activity.