Formulation: A crystalline solid
Formal Name: N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-1H-pyrazole-4-carboxamide
Purity: ≥95%
Formula Markup: C18H19N5O2
Formula Weight: 337,4
Shelf life (days): 730
CAS Number: 2364554-48-1
Notes: Aficamten is an inhibitor of cardiac myosin ATPase (IC50 = 1.26 µM for the bovine enzyme).{58958} It reduces fractional shortening in isolated rat cardiac ventricular myocytes (IC50 = 7.9 µM) and in rats in a dose-dependent manner.