Formulation: A solid
Formal Name: (2S)-1-[3,5-bis[[2,6-dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-2,4,6-trihydroxyphenyl]-2-methyl-1-butanone
Purity: ≥98%
Formula Markup: C37H46O12
Formula Weight: 682,8
Shelf life (days): 1460
CAS Number: 55576-66-4
Notes: Agrimol B is a polyphenol that has been found in A. pilosa with adipogenesis inhibitory and anticancer activities.{62704,62705} It induces nuclear translocation of sirtuin 1 (SIRT1) and reduces expression of peroxisome proliferator-activated receptor γ (PPARγ), C/EBPα, and fatty acid synthase (FASN) in 3T3-L1 adipocytes when used at a concentration of 10 µM. Agrimol B reduces lipid droplet accumulation in 3T3-L1 adipocytes (IC50 = 3.35 µM). It is cytotoxic to PC3 prostate and A549 lung cancer cells in vitro and reduces tumor volume in a PC3 mouse xenograft model when administered at a dose of 10 mg/kg.{62705}
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