Formulation: A crystalline solid
Formal Name: N′-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methyl-methanimidamide
Purity: ≥98%
Formula Markup: C19H23N3
Formula Weight: 293,4
Shelf life (days): 1460
CAS Number: 33089-61-1
Notes: Amitraz is a formamidine acaricide.{52328} It induces mortality and reduces fecundity in adult R. annulatus when used at a concentration of 300 ppm. It is lethal to adult H. bipinosa (LC50 = 181 ppm). Amitraz (100 µM) reduces viability of primary rat hippocampal cells.{52329} In vivo, amitraz (170 mg/kg) increases malondialdehyde (MDA) and nitric oxide (NO) levels and decreases superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities in rat liver, kidney, brain, spleen, and testis.{52330} Dietary administration of amitraz reduces larval weight and larval and pupal survival in honey bee (A. mellifera) populations.{52331} Formulations containing amitraz have been used as insecticides in residential, agricultural, and veterinary settings.
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