Formulation: A solid
Formal Name: (αR)-2′-(aminocarbonyl)-α-methyl-5′-(phenylmethyl)-[1,1′-biphenyl]-3-propanoic acid
Purity: ≥98%
Formula Markup: C24H23NO3
Formula Weight: 373,4
Shelf life (days): 730
CAS Number: 1845753-81-2
Notes: AZD 2716 is an inhibitor of secretory phospholipase A2 (sPLA2; IC50s = 0.01, 0.04, and 0.4 µM for sPLA2-IIa, -V, and -X, respectively).{64524} It inhibits sPLA2 activity in atherosclerotic plaque homogenates isolated from patients with coronary artery disease (IC50 = 56 nM).