FL-411, CAS 2118944-88-8

Formulation: A solid

Formal Name: 5,6,7,8-tetrahydro-2-(4-hydroxy-3,5-dimethylphenyl)-7-methyl-pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(1H)-one

Purity: ≥98%

Formula Markup: C18H19N3O2S

Formula Weight: 341,4

Shelf life (days): 1460

CAS Number: 2118944-88-8

Notes: FL-411 is an inhibitor of bromodomain-containing protein 4 (BRD4; IC50 = 0.43 µM).{67309} It is selective for BRD4 over BRD2 and BRD3 (IC50s = 24.6 and >100 µM, respectively). FL-411 inhibits the proliferation of MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 5.48 and 8.29 µM, respectively) and induces autophagy in the same cells when used at concentrations of 3, 10, and 150 µM.

• SKU: CAY37547-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37547-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe