Guanosine-5'-O-(2-thiodiphosphate) (sodium salt)

Formulation: A solution in water

Formal Name: 5′-guanylic acid, monoanhydride with phosphorothioic acid, trisodium salt

Purity: ≥95%

Formula Markup: C10H12N5O10P2S • 3Na

Formula Weight: 525,2

Shelf life (days): 730

Notes: Guanosine-5'-O-(2-thiodiphosphate) is a non-hydrolyzable derivative of GDP (Item No. 31704) and an inhibitor of adenylyl cyclase (AC; Ki = 600 nM).{64906} It is also a partial activator of AC when GTP is absent in rat cerebral cortex membranes (EC50 = 400 nM).{64907} Guanosine-5'-O-(2-thiodiphosphate) (1 µM) prevents norepinephrine-induced nitric oxide (NO) release in cardiac ventricular myocytes.{64905} It reduces female opossum urine-induced firing frequency of olfactory mitral/tufted neuronal cells in male opossums when administered at a concentration of 100 µM.{64908}

• SKU: CAY38379
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38379-2.3
• Package Unit: 2.3 mg
• Quantity Unit: STK
• Application: Reinstoffe