Indolimine-214

Shelf life (days): 365.0

Formulation: A neat oil

Formal Name: (E)-1-(1H-indol-3-yl)-N-isopentylmethanimine

Purity: ≥98%

Formula Markup: C14H18N2

Formula Weight: 214.3062

Notes: Indolimine-214 is a metabolite of M. morganii, a bacterium that is increased in the gut microbiome of patients with inflammatory bowel disease (IBD) and colorectal cancer (CRC).{67201} Indolimine-214 (25 and 100 µg/ml) increases γH2AX levels in HeLa cells and increases the tail DNA percentage in a comet assay using HeLa cells when used at a concentration of 100 µg/ml, both markers of DNA damage, but does not induce DNA damage when used alone in a circular pUC19 plasmid-based genotoxicity assay.

• SKU: CAY37953-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37953-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe