Formulation: A solid
Purity: ≥98%
Formula Markup: C12H3Cl5O
Formula Weight: 340,4
Shelf life (days): 1460
CAS Number: 57117-41-6
Notes: 1,2,3,7,8-Pentachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF). It induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 2.54 and 3.06 nM, respectively).{69319} 1,2,3,7,8-Pentachlorodibenzofuran has been found in the soil near municipal waste incinerators and in freshwater fish.{51242,69320} It accumulates in the liver, fat, and skin in mice when administered at a dose of 30 ng/kg per day.{69324} 1,2,3,7,8-Pentachlorodibenzofuran (100, 150, and 200 µg/kg) decreases maternal weight and increases the percentage of mouse fetuses with cleft palates or hydronephrosis in pregnant dams.{69323}
English
Deutsch
