Formulation: A solid
Purity: ≥90%
Formula Markup: C12H4Cl4O
Formula Weight: 306
Shelf life (days): 1460
CAS Number: 51207-31-9
Notes: 2,3,7,8-Tetrachlorodibenzofuran is a polychlorinated dibenzofuran and dioxin.{51241} It is a byproduct in the synthesis of polychlorinated biphenyls and produced by municipal waste incinerators and open burn sites.{51241,51242} 2,3,7,8-Tetrachlorodibenzofuran (1 µg/kg per day) increases hepatic levels of triglycerides, phospholipids, and ceramides and induces hepatic endoplasmic reticulum stress in mice.{51243} It induces weight loss and mortality in guinea pigs when administered at a dose of 10 µg/kg.{51244} Intraperitoneal administration of 2,3,7,8-tetrachlorodibenzofuran (0.4 mg/kg) increases the number of fetal mice with cleft palates, as well as induces kidney swelling and increases the number of reabsorbed or dead fetuses in pregnant dams.{51240}
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