Formulation: A solid
Formal Name: 2'-deoxy-adenosine 5'-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt, monosodium salt
Purity: ≥95%
Formula Markup: C21H26N7O13P2 • Na
Formula Weight: 669,4
Shelf life (days): 730
CAS Number: 1514900-83-4
Notes: 2'-deoxy NAD+ is a transient receptor potential melastatin 2 (TRPM2) agonist.{51245} It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-deoxy NAD+ has been found in Jurkat T cells. It also is a substrate of poly(ADP-ribose) transferases (PARPs) for the ADP-ribosylation of non-histone proteins in nuclei isolated from HeLa cells and rat livers.{69310}