2′-O-Methyluridine, CAS 2140-76-3

Formulation: A solid

Formal Name: 2′-O-methyl-uridine

Purity: ≥98%

Formula Markup: C10H14N2O6

Formula Weight: 258,2

Shelf life (days): 1460

CAS Number: 2140-76-3

Notes: 2′-O-Methyluridine is a modified nucleoside that has been found in T. thermophila tRNA.{65558} Incorporation of 2′-O-methyluridine into siRNA targeting the gene encoding apolipoprotein B (ApoB) decreases ApoB protein levels in HepG2 cells and prevents the production of IFN-α in isolated human peripheral blood mononuclear cells (PBMCs) compared with siRNA containing only native nucleosides.{65559} Serum levels of 2′-O-methyluridine are decreased in patients with breast cancer.{65560}

• SKU: CAY36520-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36520-25
• Package Unit: 25 g
• Quantity Unit: STK
• Application: Reinstoffe