Formulation: A solid
Formal Name: 3′-deoxy-uridine
Purity: ≥98%
Formula Markup: C9H12N2O5
Formula Weight: 228,2
Shelf life (days): 1460
CAS Number: 7057-27-4
Notes: 3′-Deoxyuridine is a dehydroxylated derivative of uridine (Item No. 20300).{65673} It inhibits T. gondii uridine phosphorylase (apparent Ki = 2.459 mM). 3′-Deoxyuridine decreases the proliferation of CCRF CEM and L1210 human leukemia, P388 mouse leukemia, and S180 mouse sarcoma cells (EC50s = 25, 5, 2.5, and 15 µM, respectively).{65674} It reduces the infection rate and number of T. cruzi amastigotes in HeLa cells when used at a concentration of 1 µM.{65675} 3′-Deoxyuridine (500 µM) is less effective than 2′-deoxyuridine (Item No. 27803) at inducing sodium currents in X. laevis oocytes expressing human concentrative nucleoside transporter 1 (CNT 1) or CNT 3.{65676}
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