Formulation: A solid
Formal Name: 4-(2-propen-1-yl)-1,2-benzenediol
Purity: ≥98%
Formula Markup: C9H10O2
Formula Weight: 150,2
Shelf life (days): 1460
CAS Number: 1126-61-0
Notes: 4-Allylcatechol is a phenol that has been found in P. betle and has diverse biological activities.{68375,68376,68377,68378} It scavenges DPPH (Item No. 14805) radicals, reduces the formation of thiobarbituric acid reactive substances (TBARS), and inhibits xanthine oxidase in cell-free assays (IC50s = 20.17, 2, and 16.7 µM, respectively).{68375,68376} 4-Allylcatechol is cytotoxic to HT-29 colon cancer cells (IC50 = 30 µg/ml).{68377} It reduces paw edema and arthritic paw tissue homogenate levels of IL-1β, prostaglandin E2 (PGE2; Item No. 14010), leukotriene B4 (LTB4; Item No. 20110), and nitric oxide (NO) in a mouse model of steam-killed M. tuberculosis-induced arthritis when administered at a dose of 4 mg/kg.{68378} 4-Allylcatechol has been used as a precursor in the synthesis of, and is a metabolite of, safrole.{48070,68379}
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