Notes: 6-Thioguanosine is a thiopurine nuceloside.{64938} Preincubation of 6-thioguanosine (10 and 100 µM, respectively) decreases uridine and methionine incorporation into ribosomal RNA in Novikoff-Hepatoma cells. It inhibits the germination of B. anthracis spores (Ki = 98 µM) and prevents spore-induced cytotoxicity in RAW 264.7 macrophages in a concentration-dependent manner.{64939} 6-Thioguanosine is active against E. coli (IC50 = 2 µM).{64940} It reduces the proliferation of MOLT-4 leukemia cells (IC50 = 0.19 µM).{64941}