Adenosine-5'-O-(2-thiodiphosphate) (sodium salt)

Adenosine-5'-O-(2-thiodiphosphate) (sodium salt)
SKU
CAY38360
Packaging Unit
2,2 mg
Manufacturer
Cayman Chemical

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Formulation: A solution in water

Formal Name: 5′-adenylic acid, anhydride with phosphorothioic acid, trisodium salt

Purity: ≥95%

Formula Markup: C10H12N5O9P2S • 3Na

Formula Weight: 509,2

Shelf life (days): 730

Notes: Adenosine-5'-O-(2-thiodiphosphate) is an agonist of purinergic P2Y receptors.{68312} It increases glucose-stimulated insulin release in isolated rat pancreas when used at concentrations ranging from 49.5 to 495 nM. Adenosine-5'-O-(2-thiodiphosphate) (1.5 µM) induces vasodilation in isolated rat pancreas and relaxation in isolated rat aortic rings precontracted by serotonin (5-HT; Item No. 14332) with an EC50 value of 0.09 µM.{68313} It increases insulin secretion and reduces elevated glucose levels in fasted dogs when administered at a dose of 0.1 mg/kg.{68314}
More Information
SKU CAY38360
Manufacturer Cayman Chemical
Manufacturer SKU 38360-2.2
Green Labware No
Package Unit 2,2 mg
Quantity Unit STK
Application Reinstoffe
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