Formulation: A solid
Formal Name: (3α,5α)-3-hydroxy-cholan-24-oic-2,2,4,4-d4 acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C24H36D4O3
Formula Weight: 380,6
Shelf life (days): 1460
Notes: Allolithocholic acid-d4 is intended for use as an internal standard for the quantification of allolithocholic acid (Item No. 38158) by GC- or LC-MS. Allolithocholic acid is a secondary allomonohydroxy bile acid.{53938} It activates large-conductance calcium-activated potassium channels (BK/KCas; EC50 = 44.21 µM in Xenopus oocytes expressing the rat channel). Fecal levels of allolithocholic acid are increased in patients with colorectal cancer.{49772} Allolithocholic acid has also been found in the urine of infants with biliary atresia.{49773}