Formulation: A solid
Formal Name: N,N-dimethyl-3-[[1-(phenylmethyl-d6)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride
Purity: ≥98%
Formula Markup: C19H17D6N3O • HCl
Formula Weight: 351,9
Shelf life (days): 1460
CAS Number: 1246817-20-8
Notes: Benzydamine-d6 is intended for use as an internal standard for the quantification of benzydamine by GC- or LC-MS. Benzydamine is a non-steroidal anti-inflammatory drug (NSAID).{51570} It inhibits LPS-induced TNF-α and IL-1β production in isolated human peripheral blood mononuclear cells (PBMCs) when used at concentrations of 12, 25, and 50 µM. In vivo, benzydamine (20 mg/kg) reduces serum and lung levels of TNF-α and IL-1β, as well as mortality, in a mouse model of LPS-induced endotoxemia.{51571} Benzydamine (100 mg/kg) reduces acetic acid-induced writhing in rats.{51572} Formulations containing benzydamine have been used as analgesics.
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