Formulation: A solid
Formal Name: butanoic acid, (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester
Purity: ≥98%
Formula Markup: C12H21NO5
Formula Weight: 259,3
Shelf life (days): 1460
CAS Number: 121104-96-9
Notes: Celgosivir is an α-glucosidase inhibitor (IC50 = 0.7 µg/ml) and a prodrug form of the α- and β-glucosidase inhibitor castanospermine (Item No. 11313).{69244,20414} It reduces bovine viral diarrhea virus (BVDV) levels in a plaque formation assay (IC50 = 16 mM) and increases the survival of bovine kidney (MDBK) cells infected with BVDV (IC50 = 47 µM).{69245} Intraperitoneal administration of celgosivir (50 mg/kg twice daily) reduces viremia and increases the survival of mice infected with a lethal dose of dengue virus.{69246}