Notes: Indole-3-lactic acid is a metabolite of tryptophan (Item Nos. 31210 / 29600).{65529} It is formed from tryptophan by gut microbiota. Indole-3-lactic acid (0.1-10 mM) inhibits LPS-induced production of IL-8 in Caco-2 intestinal epithelial cells. It reduces colon tumor number and size in cancer-prone Apc+/Min mice when administered at a dose of 20 mg/kg.{65530}