Formulation: A solid
Formal Name: L-arginine-guanidino,1,2,3,4,5-13C6 monohydrochloride
Purity: ≥95%
Formula Markup: [13C]6H14N4O2 • HCl
Formula Weight: 216,6
Shelf life (days): 1460
CAS Number: 201740-91-2
Notes: L-Arginine-13C6 is intended for use as an internal standard for the quantification of L-arginine (Item No. 23703) by GC- or LC-MS. L-Arginine is an amino acid and a precursor of nitric oxide (NO).{41250} L-Arginine is a substrate for NO synthase that is oxidized to form NO and L-citrulline. It enhances NO release induced by bradykinin (Item No. 37408) or A23187 (Item No. 11016) in porcine aortic endothelial cells.{41249} L-Arginine (30 and 300 mg/kg, i.v.) induces dilation of pial arterioles and increases cerebral blood flow in normotensive and spontaneously hypertensive rats.{41248} It also reduces infarct size by 35 and 28% in normotensive and spontaneously hypertensive rats, respectively, following middle cerebral artery occlusion.