LOC1886, CAS 951948-38-2

Formulation: A crystalline solid

Formal Name: 1H-imidazol-1-yl(4-methoxy-1H-indol-2-yl)-methanone

Purity: ≥95%

Formula Markup: C13H11N3O2

Formula Weight: 241,2

Shelf life (days): 730

CAS Number: 951948-38-2

Notes: LOC1886 is an inhibitor of glutathione peroxidase 4 (GPX4; Ki = 102 µM).{49780} It covalently binds to GPX4U46C and inhibits GPX4-mediated reduction of phospholipid hydroperoxides in HT-1080 cell lysates when used at a concentration of 100 µM. LOC1886 (100 µM) increases lipid peroxidation in HT-1080 cells, an effect that can be rescued by the ferroptosis inhibitor ferrostatin-1 (Item No. 17729).

• SKU: CAY38026-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38026-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe