Formulation: A solid
Formal Name: N-[2-(1-pyrrolidinyl)phenyl]-1,2-benzisothiazol-3-amine, 1,1-dioxide
Purity: ≥98%
Formula Markup: C17H17N3O2S
Formula Weight: 327,4
Shelf life (days): 1460
CAS Number: 874590-32-6
Notes: M1001 is a modulator of hypoxia-inducible factor-2α (HIF-2α).{69241} It stabilizes the aryl hydrocarbon receptor nuclear translocator (ARNT) and HIF-2α protein-protein interaction and promotes the gene expression of HIF-2α targets VEGF-A, CCND1, SLC2A1, and NDRG1, in 786-O cells when used at a concentration of 10 µM.