Negamycin (hydrochloride)

Formulation: A solid

Formal Name: N-((3R,5R)-3,6-diamino-5-hydroxyhexanamido)-N-methylglycine, monohydrochloride

Purity: ≥80%

Formula Markup: C9H20N4O4 • HCl

Formula Weight: 284,7

Shelf life (days): 1460

Notes: Negamycin is an antibiotic originally found in Streptomyces.{68273} It is active against various species of bacteria, including E. coli, S. typhosa, and K. pneumoniae, when used at concentrations ranging from 3.12 to 100 µg/ml. Negamycin (250 μM) stabilizes the interaction between tRNA and ribosomes and decreases the rate of mRNA translation.{68274} It also restores the auditory brainstem response to sound tones in a dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy (DMD) when administered at a dose of 100 mg/kg.{68275}

• SKU: CAY37796-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37796-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe