Formulation: A solid
Formal Name: α-(aminomethyl)-4-hydroxy-3-methoxy-benzenemethanol, monohydrochloride
Purity: ≥95%
Formula Markup: C9H13NO3 • HCl
Formula Weight: 219,7
Shelf life (days): 1460
CAS Number: 1011-74-1
Notes: Normetanephrine is an active metabolite of norepinephrine.{32483,66603,66604} It is formed from norepinephrine by catechol-O-methyltransferase (COMT).{32483} Normetanephrine induces contractions in isolated rabbit aortic strips in a concentration-dependent manner.{66603} It inhibits norepinephrine uptake in isolated rat heart (IC50 = 200 µM).{66604} Plasma levels of normetanephrine are increased in patients with von Hippel-Lindau disease and pheochromocytomas compared with patients with von Hippel-Lindau disease without pheochromocytomas.{66605} It has been used as a marker of authentic human urine specimens.{62138}
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