Formulation: A solution in methanol
Formal Name: ethyl ((R)-5-chloro-8-hydroxy-3-(methyl-13C)-1-oxoisochromane-7-carbonyl-13C10)-L-phenylalaninate-13C9
Purity: ≥98%
Formula Markup: C2[13C]20H22ClNO6
Formula Weight: 451,7
Shelf life (days): 730
Notes: Ochratoxin C-13C20 (OTC-13C20) is intended for use as an internal standard for the quantification of ochratoxin C (Item No. 20183) by GC- or LC-MS. OTC is a mycotoxin that has been found in Aspergillus and is an active metabolite of OTA (Item No. 11439).{69613,51590} It is formed from OTA by gut microbiota, however, OTA can also be formed from OTC in vivo.{51590,31745} OTC inhibits the proliferation and differentiation of THP-1 monocytes (IC50s = 126 and 91 ng/ml, respectively) and induces apoptosis in the same cells when used at concentrations of 100 or 1,000 ng/ml.{69613} It induces mortality in zebrafish embryos (LC50 = 0.32 nM).{69614} OTC has been found in red wine.{69615}
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