Formulation: A solid
Formal Name: 6-(3,5-dimethyl-4-isoxazolyl)-7-methoxy-3-methyl-1-(2-pyridinylmethyl)-2(1H)-quinolinone
Purity: ≥98%
Formula Markup: C22H21N3O3
Formula Weight: 375,4
Shelf life (days): 1460
CAS Number: 1801503-93-4
Notes: ODM-207 is an inhibitor of bromodomain and extra terminal domain (BET) bromodomains. It reduces the proliferation of isolated human metastatic apocrine sweat gland cancer cells (IC50 = 1.99 µM).{64925} ODM-207, in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib (Item No. 10621), decreases proliferation of, and induces DNA double-strand breaks in, isolated human metastatic apocrine sweat gland cancer cells deficient in partner and localizer of BRCA2 (PALB2; IC50 = 650 nM).