Formulation: A solid
Formal Name: 4,4′-(2,5-furandiyl)bis[N-methoxy-benzenecarboximidamide
Purity: ≥90%
Formula Markup: C20H20N4O3
Formula Weight: 364,4
Shelf life (days): 1460
CAS Number: 186953-56-0
Notes: Pafuramidine is a prodrug form of the protein arginine methyltransferase 1 (PRMT1) inhibitor furamidine (Item No. 19121).{51223} Oral administration of pafuramidine (25 mg/kg per day), in combination with the antiprotozoal benznidazole (Item No. 29090), reduces the number of circulating parasites and increases survival in a mouse model of T. cruzi infection.{51224}