PfDHODH-IN-1, CAS 183945-55-3

Formulation: A solid

Formal Name: 2-cyano-3-cyclopropyl-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-propenamide

Purity: ≥98%

Formula Markup: C14H11F3N2O2

Formula Weight: 296,2

Shelf life (days): 1460

CAS Number: 183945-55-3

Notes: PfDHODH-IN-1 is an inhibitor of dihydroorotate dehydrogenase (DHODH; IC50s = 190, 47, and 21 nM for the human, mouse, and rat enzymes, respectively) and a derivative of the DHODH inhibitor A-771726 (Item No. 14404).{64967,64968} It inhibits delayed-type hypersensitivity reactions in mice and rats when administered at doses of 30 and 10 mg/kg, respectively.{64968}

• SKU: CAY37728-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37728-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe