Formal Name: L-a-glutamyl-L-a-glutamyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-arginyl-L-a-glutamyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-leucyl-L-arginyl-L-arginyl-L-methionyl-L-alanyl-L-a-aspartyl-L-a-aspartyl-L-leucyl-L-asparaginyl-L-alanyl-L-glutaminyl-L-tyrosyl-L-a-glutamyl-L-arginine, trifluoroacetate salt
Amino Acids: EEQWAREIGAQLRRMADDLNAQYER-OH
Purity: ≥98%
Formula Markup: C128H202N42O43S / XCF3COOH
Formula Weight: 3049.29676
Notes: PUMA BH3 is a peptide comprising the BH3 domain of p53-upregulated modulator of apoptosis (PUMA) and an activator of the pro-apoptotic protein Bak.{67372} PUMA BH3 binds to Bak (Kds = 290 and 26 nM in HEPES and CHAPS buffer, respectively) and induces Bak homo-oligomerization and Bak-mediated membrane permeabilization.