Formulation: A solid
Formal Name: N-(3-carboxy-1-oxopropyl)-L-leucyl-L-leucyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C40H53N5O10 • XCF3COOH
Formula Weight: 763,9
Shelf life (days): 1460
Notes: Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate for the 20S proteasome, other chymotrypsin-like proteases, and calpains.{22991,29240} Upon enzymatic cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify protease activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.