Formulation: A solid
Formal Name: 2Z-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-3(2H)-benzofuranone
Purity: ≥98%
Formula Markup: C15H10O5
Formula Weight: 270,2
Shelf life (days): 1460
CAS Number: 120-05-8
Notes: Sulfuretin is a flavonoid that has been found in R. verniciflua and has diverse biological activities.{64922,64921,64923} It inhibits mushroom tyrosinase activity (IC50 = 13.64 µM).{64922} Sulfuretin decreases cytotoxicity induced by infectious hematopoietic necrosis virus (IHNV) in JFSP cells and viral hemorrhagic septicemia virus (VHSV) in CHSE-214 cells (EC50s = 178.2 and 197.3 µM, respectively).{64921} It decreases eosinophil, macrophage, and lymphocyte infiltration and reduces the levels of TNF-α, IL-5, IL-13, and CCL11 in bronchoalveolar lavage fluid (BALF), as well as inhibits methacholine-induced bronchoconstriction, in a mouse model of ovalbumin-induced asthma when administered at a dose of 40 µg/kg.{64923}
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