Tat-M2NX (trifluoroacetate salt)

Formulation: A solid

Purity: ≥98%

Formula Markup: C190H323N71O45S • XCF3COOH

Formula Weight: 4354,2

Shelf life (days): 1460

Notes: Tat-M2NX is a peptide antagonist of transient receptor potential melastatin 2 (TRPM2).{67380} It inhibits hydrogen peroxide-induced calcium influx in HEK293 cells expressing human TRPM2 when used at concentrations ranging from 25 to 100 µM. In vivo, Tat-M2NX (20 mg/kg) reduces brain infarct volume in male, but not female, mice in a model of stroke induced by middle cerebral artery occlusion (MCAO) when administered prior to or 3 hours-post occlusion.

• SKU: CAY37447-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37447-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe