Formulation: A solid
Formal Name: (3β,5α,22β,25S)-spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside
Purity: ≥95%
Formula Markup: C50H83NO21
Formula Weight: 1034,2
Shelf life (days): 730
CAS Number: 17406-45-0
Notes: Tomatine is a steroidal saponin that has been found in S. lycopersicum and has diverse biological activities.{65576,65577,65578,65579} It is active against a panel of 19 plant pathogenic fungi (EC50s = 13-912 µM) and inhibits the growth of L. amazonensis promastigotes (IC50 = 124 nM).{65576,65577} Tomatine (0.75, 1, and 1.5 µM) inhibits autophagy and induces apoptosis in SKOV3 ovarian cancer cells.{65578} Dietary administration of tomatine (0.1 and 0.2% w/w) decreases serum LDL levels and increases fecal cholesterol secretion in hamsters.{65579}