U-0521, CAS 5466-89-7

Formulation: A solid

Formal Name: 1-(3,4-dihydroxyphenyl)-2-methyl-1-propanone

Purity: ≥95%

Formula Markup: C10H12O3

Formula Weight: 180,2

Shelf life (days): 1460

CAS Number: 5466-89-7

Notes: U-0521 is an inhibitor of catechol-O-methyltransferase (COMT; Ki = 7.8 µM for the rat liver enzyme) and tyrosine hydroxylase (IC50 = 1 µM for the rabbit adrenal enzyme).{65383,65384} It enhances epinephrine-induced contractions of isolated rabbit atria when used at a concentration of 55 µM.{65383} U-0521 (41.5 µmol/kg) also enhances isoprenaline- or epinephrine-induced increases in blood glucose levels in pancreatectomized rats.{65385} It decreases blood pressure in spontaneously hypertensive, but not normotensive, rats when administered at a dose of 50 mg/kg.{65386}

• SKU: CAY36314-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36314-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK
• Application: Reinstoffe