MF094, CAS 2241025-68-1

Formulation: A solid

Formal Name: αS-[(cyclohexylcarbonyl)amino]-N-[5-[[(1,1-dimethylethyl)amino]sulfonyl]-1-naphthalenyl]-benzenepropanamide

Purity: ≥98%

Formula Markup: C30H37N3O4S

Formula Weight: 535,7

Shelf life (days): 1460

CAS Number: 2241025-68-1

Notes: MF094 is a ubiquitin-specific protease 30 (USP30) inhibitor (IC50 = 0.12 µM).{51275} It is selective for USP30 over 22 other USPs at 10 µM. MF094 (0.6, 1.7, and 5 µM) inhibits ubiquitinylated probe-induced active site modification of USP30 in mitochondria isolated from C2C12 myoblasts. It induces cell death in HSC-4 cells when used at the concentrations of 0.2, 0.5, 1, and 2 µM.{51276} MF094 (1 mg/kg per day) reduces tumor growth in an SCC4 squamous cell carcinoma mouse xenograft model.

• SKU: CAY37774-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37774-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe