Formulation: A solid
Formal Name: (9Z,12Z)-octadeca-9,12-dien-1-yl ((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Purity: ≥98%
Formula Markup: C39H55N6O8P
Formula Weight: 766,9
Shelf life (days): 730
CAS Number: 2719679-31-7
Notes: (±)-MMT5-14 is a derivative of remdesivir (Item No. 30354) with antiviral activity.{68222} It increases the viability of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50 = 0.4 µM), as well as Vero E6 cells infected with the Alpha, Beta, Gamma, or Delta SARS-CoV-2 variants (EC50s = 2.5, 15.9, 1.7, and 5.6 µM, respectively). (±)-MMT5-14 exhibits increased plasma and lung concentrations compared with remdesivir in hamsters when administered at a dose of 10 mg/kg.
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