Notes: N-acetyl-L-Glutamine is an acetylated form of the conditionally essential amino acid L-glutamine (Item No. 23716). It decreases infarct volume and prevents neuronal apoptosis in the substantia nigra in a rat model of cerebral ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).{65328} N-acetyl-L-Glutamine (8.28 g/animal per day) prevents decreases in body weight in protein-energy malnourished pigs.{65329} Formulations containing N-acetyl-L-glutamine have been used as dietary supplements.