N′-Nitrosonornicotine-d4, CAS 66148-19-4

Formulation: A solid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C9H7D4N3O

Formula Weight: 181,2

Shelf life (days): 1460

CAS Number: 66148-19-4

Notes: N′-Nitrosonornicotine-d4 is intended for use as an internal standard for the quantification of N′-nitrosonornicotine (Item No. 34120) by GC- or LC-MS. N′-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.{45975} It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N′-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N′-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.{61431}

• SKU: CAY35604-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35604-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung