Formulation: A solid
Formal Name: 3-([3,3′-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-benzenemethanamine
Purity: ≥98%
Formula Markup: C27H31NOS2
Formula Weight: 449,7
Shelf life (days): 1460
CAS Number: 131060-14-5
Notes: NB-598 is an inhibitor of squalene epoxidase (IC50s = 2 and 0.75 nM for dog liver and human microsomal enzymes, respectively).{68348} It selectively inhibits cholesterol synthesis over free fatty acid, triglyceride, and phospholipid synthesis in HepG2 cells at 1 µM. NB-598 (10 mg/kg per day) reduces serum cholesterol levels in dogs.