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Applications: Useful for the study of DPP activity, and for screening small molecule inhibitors of DPP4, DPP7, DPP8, DPP9, FAP, and POP for drug discovery and HTS applications. Also suitable for use with Xaa-Pro dipeptidase.
Description: The fluorogenic DPP substrate 1 is a Ala-Pro-AMC dipeptide. It can be used for the activity assays of DPP4, DPP7, DPP8, DPP9, FAP, and prolyl oligopeptidase (POP). λex 353-380 nm, λem=440-460 nm
Format: DMSO solution
Storage Stability: Stable at least 6 months from date of receipt, when stored as directed
Supplied As: 0.5 mM solution in DMSO (100 µl)
Warnings: Protect from direct exposure to light. Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Park, J.E., et al., J. Biol. Chem., 274, 36505 (1999).
2. Sun, S., et al., Protein Expr. Purif., 24, 274 (2002).
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