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Applications: Suitable for use with BPS's Fluorogenic SIRT5 Assay Kit, #50085, and to study enzyme kinetics and screen small molecule inhibitors of Sirtuin 5 for drug discovery and HTS applications.
Description: A fluorogenic, succinylated peptide substrate for Sirtuin 5. This substrate should be used in conjunction with SIRT Developer, #50089. Optimal excitation wavelength 350-380 nm, emission wavelength 440-460 nm.
Format: DMSO solution
Purity: >90% by HPLC
Storage Stability: Stable at least 6 months from date of receipt, when stored as directed at -20°C or -80°C
Supplied As: DMSO solution (50 µl @ 5 mM)
Tags: AMC
Uniprot: Q9NXA8
Warnings: Avoid freeze/thaw cycles. Protect from light.
Biosafety Level: Not applicable (BSL-1)
References: 1. Madsen, A.S. and Olsen, C.A., J. Med. Chem. 2012, 55:5582-5590.
2. Du, J., et al., Science, 11 November 2011, 334:806-809.
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