SBI-425, CAS 1451272-71-1

Formulation: A solid

Formal Name: 5-[[(5-chloro-2-methoxyphenyl)sulfonyl]amino]-3-pyridinecarboxamide

Purity: ≥98%

Formula Markup: C13H12ClN3O4S

Formula Weight: 341,8

Shelf life (days): 1460

CAS Number: 1451272-71-1

Notes: SBI-425 is an inhibitor of tissue-nonspecific alkaline phosphatase (TNAP; IC50 = 0.016 µM).{62593} It is selective for TNAP over a panel of 35 targets at 10 µM. SB-425 (10 and 30 mg/kg) increases survival and nearly completely inhibits the development of medial arterial calcification in a mouse model of chronic kidney disease-mineral bone disorder (CKD-MBD) induced by a high-adenine high-phosphate diet.{62594}

• SKU: CAY34626-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34626-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe