Sermorelin (acetate), CAS 516482-86-3

Formulation: A solid

Formal Name: 29-L-argininamide-1-29-somatoliberin (human pancreatic islet), acetate

Purity: ≥95%

Formula Markup: C149H246N44O42S • XC2H4O2

Formula Weight: 3357,9

Shelf life (days): 1460

CAS Number: 516482-86-3

Notes: Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release.{36354} Sermorelin (1 μg/kg, i.v.) increases serum GH levels in rats by approximately 17% compared with saline control after 15 minutes.{36356} It also increases GH release in pigs when administered at a dose of 250 ng/kg.{36355} Sermorelin (1 μM) increases proliferation of NCI-H727 human bronchial carcinoid cells by 30% and increases vascular endothelial growth factor (VEGF) secretion.{36357} It increases phosphorylation of focal adhesion kinase (FAK) and expression of VEGF in A549 lung cancer cells when used at a concentration of 0.1 μM.{36358} Formulations containing sermorelin have been used to diagnose and treat growth hormone deficiency.

• SKU: CAY36696-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36696-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe