Formulation: A solid
Formal Name: 2,3,4,4aR,5,9bS-hexahydro-2,8-dimethyl-1H-pyrido[4,3-b]indole
Purity: ≥98%
Formula Markup: C13H18N2
Formula Weight: 202,3
Shelf life (days): 1460
CAS Number: 85202-17-1
Notes: Stobadine is a pyridoindole antioxidant.{64440} It scavenges hydroxyl, peroxyl, and alkoxyl radicals and quenches singlet oxygen in cell-free assays. Ex vivo, stobadine (2 mg/kg) reduces lipid peroxidation induced by hypoxia and reoxygenation in rat forebrain.{64438} It improves survival in a rat model of carotid artery ligation-induced cerebral ischemia. Stobadine (1 mg/kg, i.v.) increases myocardial blood flow and decreases infarct area in a dog model of myocardial infarction induced by acute occlusion of the left coronary artery.{64440} Dietary administration of stobadine (0.05% w/w) delays the development of cataracts and reduces eye lens protein oxidation and plasma levels of malondialdehyde (MDA) in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104).{64439}
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