RG108 , CAS 48208-26-0

Product Description: RG108 is a non-nucleoside DNA methyltransferase (DMNT) inhibitor. RG108 effectively blocked DNA methyltransferases in-vitro and does not cause covalent enzyme trapping in human cell lines. RG108 significantly reduces the methylation of genomic DNA in cells at 10 μM without detectable toxicity, distinguishing it from nucleoside-based inhibitors like 5-azacytidine. Through these actions, RG108 demethylates and reactivates epigenetically silenced tumor suppressor genes.

CAS Number: 48208-26-0

Molecular Weight: 334.33

Structure: C19H14N2O4

Compound Purity: >98%

• SKU: CGSSM31-50
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: SM31-50
• Package Unit: 50 mg
• Quantity Unit: STK