rHuman IP-10 (CXCL10) Protein

rHuman IP-10 (CXCL10) Protein
SKU
ROC009-001-V69-0100
Packaging Unit
100 µg
Manufacturer
Rockland

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Application Note: IP-10 Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-IP-10 in immunological assays.

Concentration Value: 0.1 mg/ml

General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Other Performance Data: Endotoxin Level: Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. Biologic Activity: The activity is determined by its ability to chemoattract human T lymphocytes at 5 – 40 ng/mL.

Physical State: Lyophilized

Purity and Specificity: Ip-10 (CXCL10) purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Background: The chemokine IP-10 (or CXCL10) is a chemokine made by monocytes, endothelial cells and fibroblasts in response to treatment with IFNγ. IP-10 functions as a chemoattractant to cells (activated T cells and NK cells) expressing the G protein-coupled receptor, CXCR3. IP-10 plays an important role in Th1 type inflammatory diseases and autoimmune diseases such as, Hashimoto's thyroiditis, Graves' disease and Type 1 diabetes mellitus. Recombinant human IP-10 is a non-glycosylated protein, containing 77 amino acids, with a molecular weight of 8.5 kDa.

Low Endotoxin: Yes

Other: User Optimized
More Information
SKU ROC009-001-V69-0100
Manufacturer Rockland
Manufacturer SKU 009-001-V69-0100
Package Unit 100 µg
Quantity Unit STK
Conjugate Unconjugated
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